Autophagy induced by avian reovirus enhances viral replication in chickens at the early stage of infection
Identifieur interne : 000A31 ( Main/Exploration ); précédent : 000A30; suivant : 000A32Autophagy induced by avian reovirus enhances viral replication in chickens at the early stage of infection
Auteurs : Xiaosai Niu ; Chengcheng Zhang ; Yuyang Wang ; Mengjiao Guo ; Baoyang Ruan ; Xuefeng Wang ; Tianqi Wu ; Xiaorong Zhang ; Yantao WuSource :
- BMC Veterinary Research [ 1746-6148 ] ; 2019.
Abstract
Avian reovirus (ARV) is an important pathogen that can cause serious disease in poultry. Though several in vitro studies revealed some molecular mechanisms that are responsible for ARV-induced autophagy, it is still largely unknown how ARV manipulates autophagy to promote its own propagation.
In this study, we demonstrated that ARV infection triggered autophagy in chicken tissues, evident from the enhancement of LC3-I/−II conversion and the appearance of abundant autophagosomes. Moreover, viral replication and the expression of IL-1β were coupled with the process of ARV-induced autophagy in the early stage of infection. Furthermore, regulation of autophagy affected the accumulation of LC3-II, the production of ARV and the expression of IL-1β.
Altogether, our data suggest that ARV induces autophagy, which benefits its replication and dissemination in chicken tissues at the early infection stage.
The online version of this article (10.1186/s12917-019-1926-5) contains supplementary material, which is available to authorized users.
Url:
DOI: 10.1186/s12917-019-1926-5
PubMed: 31126305
PubMed Central: 6534907
Affiliations:
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uniqKey="Ruan B" first="Baoyang" last="Ruan">Baoyang Ruan</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author><author><name sortKey="Wang, Xuefeng" sort="Wang, Xuefeng" uniqKey="Wang X" first="Xuefeng" last="Wang">Xuefeng Wang</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author><author><name sortKey="Wu, Tianqi" sort="Wu, Tianqi" uniqKey="Wu T" first="Tianqi" last="Wu">Tianqi Wu</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author><author><name sortKey="Zhang, Xiaorong" sort="Zhang, Xiaorong" uniqKey="Zhang X" first="Xiaorong" last="Zhang">Xiaorong Zhang</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author><author><name sortKey="Wu, Yantao" sort="Wu, Yantao" uniqKey="Wu Y" first="Yantao" last="Wu">Yantao Wu</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">31126305</idno><idno type="pmc">6534907</idno><idno 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type="main">Autophagy induced by avian reovirus enhances viral replication in chickens at the early stage of infection</title><author><name sortKey="Niu, Xiaosai" sort="Niu, Xiaosai" uniqKey="Niu X" first="Xiaosai" last="Niu">Xiaosai Niu</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author><author><name sortKey="Zhang, Chengcheng" sort="Zhang, Chengcheng" uniqKey="Zhang C" first="Chengcheng" last="Zhang">Chengcheng Zhang</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author><author><name sortKey="Wang, Yuyang" sort="Wang, Yuyang" uniqKey="Wang Y" first="Yuyang" last="Wang">Yuyang Wang</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author><author><name sortKey="Guo, Mengjiao" sort="Guo, Mengjiao" uniqKey="Guo M" first="Mengjiao" last="Guo">Mengjiao Guo</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author><author><name sortKey="Ruan, Baoyang" sort="Ruan, Baoyang" uniqKey="Ruan B" first="Baoyang" last="Ruan">Baoyang Ruan</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author><author><name sortKey="Wang, Xuefeng" sort="Wang, Xuefeng" uniqKey="Wang X" first="Xuefeng" last="Wang">Xuefeng Wang</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author><author><name sortKey="Wu, Tianqi" sort="Wu, Tianqi" uniqKey="Wu T" first="Tianqi" last="Wu">Tianqi Wu</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author><author><name sortKey="Zhang, Xiaorong" sort="Zhang, Xiaorong" uniqKey="Zhang X" first="Xiaorong" last="Zhang">Xiaorong Zhang</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author><author><name sortKey="Wu, Yantao" sort="Wu, Yantao" uniqKey="Wu Y" first="Yantao" last="Wu">Yantao Wu</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author></analytic><series><title level="j">BMC Veterinary Research</title><idno type="eISSN">1746-6148</idno><imprint><date when="2019">2019</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Background</title><p id="Par1">Avian reovirus (ARV) is an important pathogen that can cause serious disease in poultry. Though several in vitro studies revealed some molecular mechanisms that are responsible for ARV-induced autophagy, it is still largely unknown how ARV manipulates autophagy to promote its own propagation.</p></sec><sec><title>Results</title><p id="Par2">In this study, we demonstrated that ARV infection triggered autophagy in chicken tissues, evident from the enhancement of LC3-I/−II conversion and the appearance of abundant autophagosomes. Moreover, viral replication and the expression of IL-1β were coupled with the process of ARV-induced autophagy in the early stage of infection. Furthermore, regulation of autophagy affected the accumulation of LC3-II, the production of ARV and the expression of IL-1β.</p></sec><sec><title>Conclusions</title><p id="Par3">Altogether, our data suggest that ARV induces autophagy, which benefits its replication and dissemination in chicken tissues at the early infection stage.</p></sec><sec><title>Electronic supplementary material</title><p>The online version of this article (10.1186/s12917-019-1926-5) contains supplementary material, which is available to authorized users.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="King, Amq" uniqKey="King A">AMQ King</name></author><author><name sortKey="Adams, Mj" uniqKey="Adams M">MJ Adams</name></author><author><name sortKey="Carstens, Eb" uniqKey="Carstens E">EB Carstens</name></author><author><name sortKey="Lefkowitz, Ej" uniqKey="Lefkowitz E">EJ Lefkowitz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ayalew, Le" uniqKey="Ayalew L">LE Ayalew</name></author><author><name sortKey="Gupta, A" uniqKey="Gupta A">A Gupta</name></author><author><name sortKey="Fricke, J" uniqKey="Fricke J">J Fricke</name></author><author><name sortKey="Ahmed, Ka" uniqKey="Ahmed K">KA Ahmed</name></author><author><name sortKey="Popowich, S" uniqKey="Popowich S">S Popowich</name></author><author><name sortKey="Lockerbie, B" uniqKey="Lockerbie B">B Lockerbie</name></author><author><name sortKey="Tikoo, Sk" uniqKey="Tikoo S">SK Tikoo</name></author><author><name sortKey="Ojkic, D" uniqKey="Ojkic D">D Ojkic</name></author><author><name sortKey="Gomis, S" uniqKey="Gomis S">S Gomis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nham, Eg" uniqKey="Nham E">EG Nham</name></author><author><name sortKey="Pearl, Dl" uniqKey="Pearl D">DL Pearl</name></author><author><name sortKey="Slavic, D" uniqKey="Slavic D">D Slavic</name></author><author><name sortKey="Ouckama, R" uniqKey="Ouckama R">R Ouckama</name></author><author><name sortKey="Ojkic, D" uniqKey="Ojkic D">D Ojkic</name></author><author><name sortKey="Guerin, Mt" uniqKey="Guerin M">MT Guerin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chulu, Jl" uniqKey="Chulu J">JL Chulu</name></author><author><name sortKey="Lee, Lh" uniqKey="Lee L">LH Lee</name></author><author><name sortKey="Lee, Yc" uniqKey="Lee Y">YC Lee</name></author><author><name sortKey="Liao, Sh" uniqKey="Liao S">SH Liao</name></author><author><name sortKey="Lin, Fl" uniqKey="Lin F">FL Lin</name></author><author><name sortKey="Shih, Wl" uniqKey="Shih W">WL Shih</name></author><author><name sortKey="Liu, Hj" uniqKey="Liu H">HJ Liu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lin, Hy" uniqKey="Lin H">HY Lin</name></author><author><name sortKey="Chuang, St" uniqKey="Chuang S">ST Chuang</name></author><author><name sortKey="Chen, Yt" uniqKey="Chen Y">YT Chen</name></author><author><name sortKey="Shih, Wl" uniqKey="Shih W">WL Shih</name></author><author><name sortKey="Chang, Cd" uniqKey="Chang C">CD Chang</name></author><author><name sortKey="Liu, Hj" uniqKey="Liu H">HJ Liu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lin, Py" uniqKey="Lin P">PY Lin</name></author><author><name sortKey="Liu, Hj" uniqKey="Liu H">HJ Liu</name></author><author><name sortKey="Chang, Cd" uniqKey="Chang C">CD Chang</name></author><author><name sortKey="Chang, Ci" uniqKey="Chang C">CI Chang</name></author><author><name sortKey="Hsu, Jl" uniqKey="Hsu J">JL Hsu</name></author><author><name sortKey="Liao, Mh" uniqKey="Liao M">MH Liao</name></author><author><name sortKey="Lee, Jw" uniqKey="Lee J">JW Lee</name></author><author><name sortKey="Shih, Wl" uniqKey="Shih W">WL Shih</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Meng, S" uniqKey="Meng S">S Meng</name></author><author><name sortKey="Jiang, K" uniqKey="Jiang K">K Jiang</name></author><author><name sortKey="Zhang, X" uniqKey="Zhang X">X Zhang</name></author><author><name sortKey="Zhang, M" uniqKey="Zhang M">M Zhang</name></author><author><name sortKey="Zhou, Z" uniqKey="Zhou Z">Z Zhou</name></author><author><name sortKey="Hu, M" uniqKey="Hu M">M Hu</name></author><author><name sortKey="Yang, R" uniqKey="Yang R">R Yang</name></author><author><name sortKey="Sun, C" uniqKey="Sun C">C Sun</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Duan, S" uniqKey="Duan S">S Duan</name></author><author><name sortKey="Cheng, J" uniqKey="Cheng J">J Cheng</name></author><author><name sortKey="Li, C" uniqKey="Li C">C Li</name></author><author><name sortKey="Yu, L" uniqKey="Yu L">L Yu</name></author><author><name sortKey="Zhang, X" uniqKey="Zhang X">X Zhang</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Chi, Pi" uniqKey="Chi P">PI Chi</name></author><author><name sortKey="Huang, Wr" uniqKey="Huang W">WR Huang</name></author><author><name sortKey="Lai, Ih" uniqKey="Lai I">IH Lai</name></author><author><name sortKey="Cheng, Cy" uniqKey="Cheng C">CY Cheng</name></author><author><name sortKey="Liu, Hj" uniqKey="Liu H">HJ Liu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huang, Wr" uniqKey="Huang W">WR Huang</name></author><author><name sortKey="Chiu, Hc" uniqKey="Chiu H">HC Chiu</name></author><author><name sortKey="Liao, Tl" uniqKey="Liao T">TL Liao</name></author><author><name sortKey="Chuang, Kp" uniqKey="Chuang K">KP Chuang</name></author><author><name sortKey="Shih, Wl" uniqKey="Shih W">WL Shih</name></author><author><name sortKey="Liu, Hj" uniqKey="Liu H">HJ Liu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dong, X" uniqKey="Dong X">X Dong</name></author><author><name sortKey="Levine, B" uniqKey="Levine B">B Levine</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Lin, Py" uniqKey="Lin P">PY Lin</name></author><author><name sortKey="Liu, Hj" uniqKey="Liu H">HJ Liu</name></author><author><name sortKey="Liao, Mh" uniqKey="Liao M">MH Liao</name></author><author><name sortKey="Chang, Cd" uniqKey="Chang C">CD Chang</name></author><author><name sortKey="Chang, Ci" uniqKey="Chang C">CI Chang</name></author><author><name sortKey="Cheng, Hl" uniqKey="Cheng H">HL Cheng</name></author><author><name sortKey="Lee, Jw" uniqKey="Lee J">JW Lee</name></author><author><name sortKey="Shih, Wl" uniqKey="Shih W">WL Shih</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dupont, N" uniqKey="Dupont N">N Dupont</name></author><author><name sortKey="Jiang, S" uniqKey="Jiang S">S Jiang</name></author><author><name sortKey="Pilli, M" uniqKey="Pilli M">M Pilli</name></author><author><name sortKey="Ornatowski, W" uniqKey="Ornatowski W">W Ornatowski</name></author><author><name sortKey="Bhattacharya, D" uniqKey="Bhattacharya D">D Bhattacharya</name></author><author><name sortKey="Deretic, V" uniqKey="Deretic V">V Deretic</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Niu, X" uniqKey="Niu X">X Niu</name></author><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y Wang</name></author><author><name sortKey="Min, L" uniqKey="Min L">L Min</name></author><author><name sortKey="Zhang, X" uniqKey="Zhang X">X Zhang</name></author><author><name sortKey="Wu, Y" uniqKey="Wu Y">Y Wu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Klionsky, Dj" uniqKey="Klionsky D">DJ Klionsky</name></author><author><name sortKey="Abdelmohsen, K" uniqKey="Abdelmohsen K">K Abdelmohsen</name></author><author><name sortKey="Abe, A" uniqKey="Abe A">A Abe</name></author><author><name sortKey="Abedin, Mj" uniqKey="Abedin M">MJ Abedin</name></author><author><name sortKey="Abeliovich, H" uniqKey="Abeliovich H">H Abeliovich</name></author><author><name sortKey="Arozena, Aa" uniqKey="Arozena A">AA Arozena</name></author><author><name sortKey="Adachi, H" uniqKey="Adachi H">H Adachi</name></author><author><name sortKey="Adams, Cm" uniqKey="Adams C">CM Adams</name></author><author><name sortKey="Adams, Pd" uniqKey="Adams P">PD Adams</name></author><author><name sortKey="Adeli, K" uniqKey="Adeli K">K Adeli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jones, Rc" uniqKey="Jones R">RC Jones</name></author><author><name sortKey="Islam, Mr" uniqKey="Islam M">MR Islam</name></author><author><name sortKey="Kelly, Df" uniqKey="Kelly D">DF Kelly</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tang, Kn" uniqKey="Tang K">KN Tang</name></author><author><name sortKey="Fletcher, Oj" uniqKey="Fletcher O">OJ Fletcher</name></author><author><name sortKey="Villegas, P" uniqKey="Villegas P">P Villegas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, Ys" uniqKey="Chen Y">YS Chen</name></author><author><name sortKey="Shen, Pc" uniqKey="Shen P">PC Shen</name></author><author><name sortKey="Su, Bs" uniqKey="Su B">BS Su</name></author><author><name sortKey="Liu, Tc" uniqKey="Liu T">TC Liu</name></author><author><name sortKey="Lin, Cc" uniqKey="Lin C">CC Lin</name></author><author><name sortKey="Lee, Lh" uniqKey="Lee L">LH Lee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mills, Jn" uniqKey="Mills J">JN Mills</name></author><author><name sortKey="Wilcox, Ge" uniqKey="Wilcox G">GE Wilcox</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, Yf" uniqKey="Wu Y">YF Wu</name></author><author><name sortKey="Liu, Hj" uniqKey="Liu H">HJ Liu</name></author><author><name sortKey="Shien, Jh" uniqKey="Shien J">JH Shien</name></author><author><name sortKey="Chiou, Sh" uniqKey="Chiou S">SH Chiou</name></author><author><name sortKey="Lee, Lh" uniqKey="Lee L">LH Lee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Baty, Cj" uniqKey="Baty C">CJ Baty</name></author><author><name sortKey="Sherry, B" uniqKey="Sherry B">B Sherry</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yu, L" uniqKey="Yu L">L Yu</name></author><author><name sortKey="Zhang, X" uniqKey="Zhang X">X Zhang</name></author><author><name sortKey="Wu, T" uniqKey="Wu T">T Wu</name></author><author><name sortKey="Su, J" uniqKey="Su J">J Su</name></author><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y Wang</name></author><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y Wang</name></author><author><name sortKey="Ruan, B" uniqKey="Ruan B">B Ruan</name></author><author><name sortKey="Niu, X" uniqKey="Niu X">X Niu</name></author><author><name sortKey="Wu, Y" uniqKey="Wu Y">Y Wu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sun, Y" uniqKey="Sun Y">Y Sun</name></author><author><name sortKey="Li, C" uniqKey="Li C">C Li</name></author><author><name sortKey="Shu, Y" uniqKey="Shu Y">Y Shu</name></author><author><name sortKey="Ju, X" uniqKey="Ju X">X Ju</name></author><author><name sortKey="Zou, Z" uniqKey="Zou Z">Z Zou</name></author><author><name sortKey="Wang, H" uniqKey="Wang H">H Wang</name></author><author><name sortKey="Rao, S" uniqKey="Rao S">S Rao</name></author><author><name sortKey="Guo, F" uniqKey="Guo F">F Guo</name></author><author><name sortKey="Liu, H" uniqKey="Liu H">H Liu</name></author><author><name sortKey="Nan, W" uniqKey="Nan W">W Nan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sun, Y" uniqKey="Sun Y">Y Sun</name></author><author><name sortKey="Yu, S" uniqKey="Yu S">S Yu</name></author><author><name sortKey="Ding, N" uniqKey="Ding N">N Ding</name></author><author><name sortKey="Meng, C" uniqKey="Meng C">C Meng</name></author><author><name sortKey="Meng, S" uniqKey="Meng S">S Meng</name></author><author><name sortKey="Zhang, S" uniqKey="Zhang S">S Zhang</name></author><author><name sortKey="Zhan, Y" uniqKey="Zhan Y">Y Zhan</name></author><author><name sortKey="Qiu, X" uniqKey="Qiu X">X Qiu</name></author><author><name sortKey="Tan, L" uniqKey="Tan L">L Tan</name></author><author><name sortKey="Chen, H" uniqKey="Chen H">H Chen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Du, J" uniqKey="Du J">J Du</name></author><author><name sortKey="Wang, L" uniqKey="Wang L">L Wang</name></author><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y Wang</name></author><author><name sortKey="Shen, J" uniqKey="Shen J">J Shen</name></author><author><name sortKey="Pan, C" uniqKey="Pan C">C Pan</name></author><author><name sortKey="Meng, Y" uniqKey="Meng Y">Y Meng</name></author><author><name sortKey="Yang, C" uniqKey="Yang C">C Yang</name></author><author><name sortKey="Ji, H" uniqKey="Ji H">H Ji</name></author><author><name sortKey="Dong, W" uniqKey="Dong W">W Dong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Barjesteh, N" uniqKey="Barjesteh N">N Barjesteh</name></author><author><name sortKey="Hodgins, Dc" uniqKey="Hodgins D">DC Hodgins</name></author><author><name sortKey="St Paul, M" uniqKey="St Paul M">M St Paul</name></author><author><name sortKey="Quinteiro Filho, Wm" uniqKey="Quinteiro Filho W">WM Quinteiro-Filho</name></author><author><name sortKey="Depass, C" uniqKey="Depass C">C DePass</name></author><author><name sortKey="Monteiro, Ma" uniqKey="Monteiro M">MA Monteiro</name></author><author><name sortKey="Sharif, S" uniqKey="Sharif S">S Sharif</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, Yp" uniqKey="Li Y">YP Li</name></author><author><name sortKey="Bang, Dd" uniqKey="Bang D">DD Bang</name></author><author><name sortKey="Handberg, Kj" uniqKey="Handberg K">KJ Handberg</name></author><author><name sortKey="Jorgensen, Ph" uniqKey="Jorgensen P">PH Jorgensen</name></author><author><name sortKey="Zhang, Mf" uniqKey="Zhang M">MF Zhang</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list></list><tree><noCountry><name sortKey="Guo, Mengjiao" sort="Guo, Mengjiao" uniqKey="Guo M" first="Mengjiao" last="Guo">Mengjiao Guo</name><name sortKey="Niu, Xiaosai" sort="Niu, Xiaosai" uniqKey="Niu X" first="Xiaosai" last="Niu">Xiaosai Niu</name><name sortKey="Ruan, Baoyang" sort="Ruan, Baoyang" uniqKey="Ruan B" first="Baoyang" last="Ruan">Baoyang Ruan</name><name sortKey="Wang, Xuefeng" sort="Wang, Xuefeng" uniqKey="Wang X" first="Xuefeng" last="Wang">Xuefeng Wang</name><name sortKey="Wang, Yuyang" sort="Wang, Yuyang" uniqKey="Wang Y" first="Yuyang" last="Wang">Yuyang Wang</name><name sortKey="Wu, Tianqi" sort="Wu, Tianqi" uniqKey="Wu T" first="Tianqi" last="Wu">Tianqi Wu</name><name sortKey="Wu, Yantao" sort="Wu, Yantao" uniqKey="Wu Y" first="Yantao" last="Wu">Yantao Wu</name><name sortKey="Zhang, Chengcheng" sort="Zhang, Chengcheng" uniqKey="Zhang C" first="Chengcheng" last="Zhang">Chengcheng Zhang</name><name sortKey="Zhang, Xiaorong" sort="Zhang, Xiaorong" uniqKey="Zhang X" first="Xiaorong" last="Zhang">Xiaorong Zhang</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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|type= RBID
|clé= PMC:6534907
|texte= Autophagy induced by avian reovirus enhances viral replication in chickens at the early stage of infection
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:31126305" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a ChloroquineV1
| This area was generated with Dilib version V0.6.33. |  |